BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2

Cerebral ischemia induces massive mitochondrial damage. These damaged mitochondria are cleared, thus attenuating brain injury, by mitophagy. Here, we identified the involvement of BNIP3L/NIX in cerebral ischemia-reperfusion (I-R)-induced mitophagy. Bnip3l knockout (bnip3l(−/−)) impaired mitophagy an...

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Bibliografiska uppgifter
I publikationen:Autophagy
Huvudupphovsmän: Yuan, Yang, Zheng, Yanrong, Zhang, Xiangnan, Chen, Ying, Wu, Xiaoli, Wu, Jiaying, Shen, Zhe, Jiang, Lei, Wang, Lu, Yang, Wei, Luo, Jianhong, Qin, Zhenghong, Hu, Weiwei, Chen, Zhong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2017
Ämnen:
Basic Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640199/
https://ncbi.nlm.nih.gov/pubmed/28820284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1357792
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