BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2

Cerebral ischemia induces massive mitochondrial damage. These damaged mitochondria are cleared, thus attenuating brain injury, by mitophagy. Here, we identified the involvement of BNIP3L/NIX in cerebral ischemia-reperfusion (I-R)-induced mitophagy. Bnip3l knockout (bnip3l(−/−)) impaired mitophagy an...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Yuan, Yang, Zheng, Yanrong, Zhang, Xiangnan, Chen, Ying, Wu, Xiaoli, Wu, Jiaying, Shen, Zhe, Jiang, Lei, Wang, Lu, Yang, Wei, Luo, Jianhong, Qin, Zhenghong, Hu, Weiwei, Chen, Zhong
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Basic Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640199/
https://ncbi.nlm.nih.gov/pubmed/28820284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1357792
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