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ROLE OF BNIP3 AND NIX IN CELL DEATH, AUTOPHAGY, AND MITOPHAGY

BNIP3 and NIX are proteins related to the BH3-only family, which induce both cell death and autophagy. Consistent with their ability to induce cell death, BNIP3 and NIX are implicated in the pathogenesis of cancer and heart disease. In tumor cells, BNIP3 and NIX are regulated by hypoxia, and the der...

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Detalhes bibliográficos
Main Authors: Zhang, Ji, Ney, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768230/
https://ncbi.nlm.nih.gov/pubmed/19229244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.16
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