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BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects

Stress-induced glucocorticoids disturb mitochondrial bioenergetics and dynamics; however, instead of being removed via mitophagy, the damaged mitochondria accumulate. Therefore, we investigate the role of glucocorticoids in mitophagy inhibition and subsequent synaptic defects in hippocampal neurons,...

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Foilsithe in:Nat Commun
Main Authors: Choi, Gee Euhn, Lee, Hyun Jik, Chae, Chang Woo, Cho, Ji Hyeon, Jung, Young Hyun, Kim, Jun Sung, Kim, Seo Yihl, Lim, Jae Ryong, Han, Ho Jae
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817668/
https://ncbi.nlm.nih.gov/pubmed/33473105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20679-y
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