Melatonin activates ABCA1 via the BiP/NRF1 pathway to suppress high-cholesterol-induced apoptosis of mesenchymal stem cells

BACKGROUND: Retarded wound healing in patients with obesity contributes to a risk of complications associated with vascular insufficiency and oxidative stress. The high cholesterol levels of patients with obesity are associated with apoptosis of engrafted umbilical cord blood-derived mesenchymal ste...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Kim, Jun Sung, Jung, Young Hyun, Lee, Hyun Jik, Chae, Chang Woo, Choi, Gee Euhn, Lim, Jae Ryong, Kim, Seo Yihl, Lee, Joo Eun, Han, Ho Jae
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866631/
https://ncbi.nlm.nih.gov/pubmed/33546749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02181-4
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