BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2

Cerebral ischemia induces massive mitochondrial damage. These damaged mitochondria are cleared, thus attenuating brain injury, by mitophagy. Here, we identified the involvement of BNIP3L/NIX in cerebral ischemia-reperfusion (I-R)-induced mitophagy. Bnip3l knockout (bnip3l(−/−)) impaired mitophagy an...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Yuan, Yang, Zheng, Yanrong, Zhang, Xiangnan, Chen, Ying, Wu, Xiaoli, Wu, Jiaying, Shen, Zhe, Jiang, Lei, Wang, Lu, Yang, Wei, Luo, Jianhong, Qin, Zhenghong, Hu, Weiwei, Chen, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640199/
https://ncbi.nlm.nih.gov/pubmed/28820284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1357792
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