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BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2
Cerebral ischemia induces massive mitochondrial damage. These damaged mitochondria are cleared, thus attenuating brain injury, by mitophagy. Here, we identified the involvement of BNIP3L/NIX in cerebral ischemia-reperfusion (I-R)-induced mitophagy. Bnip3l knockout (bnip3l(−/−)) impaired mitophagy an...
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| Publicat a: | Autophagy |
|---|---|
| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640199/ https://ncbi.nlm.nih.gov/pubmed/28820284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1357792 |
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