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Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy

Overcoming metabolic stress is a critical step in tumorigenesis. Acetyl coenzyme A (acetyl-CoA) converted from glucose or acetate is a substrate used for histone acetylation to regulate gene expression. However, how acetyl-CoA is produced under nutritional stress conditions is unclear. Herein we rep...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Autophagy
Prif Awduron: Li, Xinjian, Qian, Xu, Lu, Zhimin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640193/
https://ncbi.nlm.nih.gov/pubmed/28820290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1349581
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