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Protein kinase activity of the glycolytic enzyme PGK1 regulates autophagy to promote tumorigenesis

Macroautophagy/autophagy is a cellular defense response to stress conditions and is crucial for cell homeostasis maintenance. However, the precise mechanism underlying autophagy initiation, especially in response to glutamine deprivation and hypoxia, is yet to be explored. We recently discovered tha...

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Опубликовано в: :Autophagy
Главные авторы: Qian, Xu, Li, Xinjian, Lu, Zhimin
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529066/
https://ncbi.nlm.nih.gov/pubmed/28486006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1313945
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