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Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy
Overcoming metabolic stress is a critical step in tumorigenesis. Acetyl coenzyme A (acetyl-CoA) converted from glucose or acetate is a substrate used for histone acetylation to regulate gene expression. However, how acetyl-CoA is produced under nutritional stress conditions is unclear. Herein we rep...
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| Publicado en: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640193/ https://ncbi.nlm.nih.gov/pubmed/28820290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1349581 |
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