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DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints

Maintenance of genome stability depends on efficient, accurate repair of DNA damage. DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage, with the potential to cause mutation, chromosomal rearrangement, and genomic instability that could contribute to cancer. DSB damage can...

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Publicado en:Trends Cell Biol
Autores principales: You, Zhongsheng, Bailis, Julie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640159/
https://ncbi.nlm.nih.gov/pubmed/20444606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2010.04.002
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