And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance

To prevent genomic instability, cells respond to DNA lesions by blocking cell cycle progression and initiating DNA repair. Homologous recombination repair of DNA breaks requires CtIP-dependent resection of the DNA ends, which is thought to play a key role in activation of CHK1 kinase to induce the c...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Chen, Yali, Liu, Hailong, Zhang, Haoxing, Sun, Changqing, Hu, Zhaohua, Tian, Qingsong, Peng, Changmin, Jiang, Pei, Hua, Hui, Li, Xinzhi, Pei, Huadong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389581/
https://ncbi.nlm.nih.gov/pubmed/27940552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1212
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