And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance

To prevent genomic instability, cells respond to DNA lesions by blocking cell cycle progression and initiating DNA repair. Homologous recombination repair of DNA breaks requires CtIP-dependent resection of the DNA ends, which is thought to play a key role in activation of CHK1 kinase to induce the c...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Chen, Yali, Liu, Hailong, Zhang, Haoxing, Sun, Changqing, Hu, Zhaohua, Tian, Qingsong, Peng, Changmin, Jiang, Pei, Hua, Hui, Li, Xinzhi, Pei, Huadong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389581/
https://ncbi.nlm.nih.gov/pubmed/27940552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1212
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