And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance

To prevent genomic instability, cells respond to DNA lesions by blocking cell cycle progression and initiating DNA repair. Homologous recombination repair of DNA breaks requires CtIP-dependent resection of the DNA ends, which is thought to play a key role in activation of CHK1 kinase to induce the c...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Chen, Yali, Liu, Hailong, Zhang, Haoxing, Sun, Changqing, Hu, Zhaohua, Tian, Qingsong, Peng, Changmin, Jiang, Pei, Hua, Hui, Li, Xinzhi, Pei, Huadong
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389581/
https://ncbi.nlm.nih.gov/pubmed/27940552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1212
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