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DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
Maintenance of genome stability depends on efficient, accurate repair of DNA damage. DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage, with the potential to cause mutation, chromosomal rearrangement, and genomic instability that could contribute to cancer. DSB damage can...
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Publicado no: | Trends Cell Biol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640159/ https://ncbi.nlm.nih.gov/pubmed/20444606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2010.04.002 |
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