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Pancreatic and snake venom presynaptically active phospholipases A(2) inhibit nicotinic acetylcholine receptors

Phospholipases A(2) (PLA(2)s) are enzymes found throughout the animal kingdom. They hydrolyze phospholipids in the sn-2 position producing lysophospholipids and unsaturated fatty acids, agents that can damage membranes. PLA(2)s from snake venoms have numerous toxic effects, not all of which can be e...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Vulfius, Catherine A., Kasheverov, Igor E., Kryukova, Elena V., Spirova, Ekaterina N., Shelukhina, Irina V., Starkov, Vladislav G., Andreeva, Tatyana V., Faure, Grazyna, Zouridakis, Marios, Tsetlin, Victor I., Utkin, Yuri N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638340/
https://ncbi.nlm.nih.gov/pubmed/29023569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186206
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