Pancreatic and snake venom presynaptically active phospholipases A(2) inhibit nicotinic acetylcholine receptors

Phospholipases A(2) (PLA(2)s) are enzymes found throughout the animal kingdom. They hydrolyze phospholipids in the sn-2 position producing lysophospholipids and unsaturated fatty acids, agents that can damage membranes. PLA(2)s from snake venoms have numerous toxic effects, not all of which can be e...

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Publicado en:PLoS One
Autores principales: Vulfius, Catherine A., Kasheverov, Igor E., Kryukova, Elena V., Spirova, Ekaterina N., Shelukhina, Irina V., Starkov, Vladislav G., Andreeva, Tatyana V., Faure, Grazyna, Zouridakis, Marios, Tsetlin, Victor I., Utkin, Yuri N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638340/
https://ncbi.nlm.nih.gov/pubmed/29023569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186206
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