Pancreatic and snake venom presynaptically active phospholipases A(2) inhibit nicotinic acetylcholine receptors

Phospholipases A(2) (PLA(2)s) are enzymes found throughout the animal kingdom. They hydrolyze phospholipids in the sn-2 position producing lysophospholipids and unsaturated fatty acids, agents that can damage membranes. PLA(2)s from snake venoms have numerous toxic effects, not all of which can be e...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Vulfius, Catherine A., Kasheverov, Igor E., Kryukova, Elena V., Spirova, Ekaterina N., Shelukhina, Irina V., Starkov, Vladislav G., Andreeva, Tatyana V., Faure, Grazyna, Zouridakis, Marios, Tsetlin, Victor I., Utkin, Yuri N.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638340/
https://ncbi.nlm.nih.gov/pubmed/29023569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186206
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