Pancreatic and snake venom presynaptically active phospholipases A(2) inhibit nicotinic acetylcholine receptors

Phospholipases A(2) (PLA(2)s) are enzymes found throughout the animal kingdom. They hydrolyze phospholipids in the sn-2 position producing lysophospholipids and unsaturated fatty acids, agents that can damage membranes. PLA(2)s from snake venoms have numerous toxic effects, not all of which can be e...

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Udgivet i:PLoS One
Main Authors: Vulfius, Catherine A., Kasheverov, Igor E., Kryukova, Elena V., Spirova, Ekaterina N., Shelukhina, Irina V., Starkov, Vladislav G., Andreeva, Tatyana V., Faure, Grazyna, Zouridakis, Marios, Tsetlin, Victor I., Utkin, Yuri N.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638340/
https://ncbi.nlm.nih.gov/pubmed/29023569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186206
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