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Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABA(A) and Nicotinic Acetylcholine Receptors
Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABA(A) receptors (GABA(A)Rs) with different efficacy, an important role of the TFTs central loop in binding to these receptors...
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| Udgivet i: | Toxins (Basel) |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7924340/ https://ncbi.nlm.nih.gov/pubmed/33672715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13020164 |
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