Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABA(A) and Nicotinic Acetylcholine Receptors

Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABA(A) receptors (GABA(A)Rs) with different efficacy, an important role of the TFTs central loop in binding to these receptors...

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Vydáno v:Toxins (Basel)
Hlavní autoři: Son, Lina, Kryukova, Elena, Ziganshin, Rustam, Andreeva, Tatyana, Kudryavtsev, Denis, Kasheverov, Igor, Tsetlin, Victor, Utkin, Yuri
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924340/
https://ncbi.nlm.nih.gov/pubmed/33672715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13020164
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