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Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABA(A) and Nicotinic Acetylcholine Receptors

Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABA(A) receptors (GABA(A)Rs) with different efficacy, an important role of the TFTs central loop in binding to these receptors...

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Dades bibliogràfiques
Publicat a:Toxins (Basel)
Autors principals: Son, Lina, Kryukova, Elena, Ziganshin, Rustam, Andreeva, Tatyana, Kudryavtsev, Denis, Kasheverov, Igor, Tsetlin, Victor, Utkin, Yuri
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924340/
https://ncbi.nlm.nih.gov/pubmed/33672715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13020164
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