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Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABA(A) and Nicotinic Acetylcholine Receptors
Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABA(A) receptors (GABA(A)Rs) with different efficacy, an important role of the TFTs central loop in binding to these receptors...
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| Publicado no: | Toxins (Basel) |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7924340/ https://ncbi.nlm.nih.gov/pubmed/33672715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13020164 |
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