Inhibition of the Nicotinic Acetylcholine Receptors by Cobra Venom α-Neurotoxins: Is There a Perspective in Lung Cancer Treatment?

Nicotine exerts its oncogenic effects through the binding to nicotinic acetylcholine receptors (nAChRs) and the activation of downstream pathways that block apoptosis and promote neo-angiogenesis. The nAChRs of the α7 subtype are present on a wide variety of cancer cells and their inhibition by cobr...

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Detaylı Bibliyografya
Asıl Yazarlar: Alama, Angela, Bruzzo, Cristina, Cavalieri, Zita, Forlani, Alessandra, Utkin, Yuri, Casciano, Ida, Romani, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113800/
https://ncbi.nlm.nih.gov/pubmed/21695184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020695
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