Synthetic Analogs of Curcumin Modulate the Function of Multidrug Resistance–Linked ATP-Binding Cassette Transporter ABCG2

Multidrug resistance (MDR) caused by the overexpression of ATP-binding cassette (ABC) transporters in cancer cells is a major obstacle in cancer chemotherapy. Previous studies have shown that curcumin, a natural product and a dietary constituent of turmeric, inhibits the function of MDR-related ABC...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Murakami, Megumi, Ohnuma, Shinobu, Fukuda, Michihiro, Chufan, Eduardo E., Kudoh, Katsuyoshi, Kanehara, Keigo, Sugisawa, Norihiko, Ishida, Masaharu, Naitoh, Takeshi, Shibata, Hiroyuki, Iwabuchi, Yoshiharu, Ambudkar, Suresh V., Unno, Michiaki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637816/
https://ncbi.nlm.nih.gov/pubmed/28904007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.076000
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