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Physiologically Based Pharmacokinetic Model of the CYP2D6 Probe Atomoxetine: Extrapolation to Special Populations and Drug-Drug Interactions

Physiologically based pharmacokinetic (PBPK) modeling of drug disposition and drug-drug interactions (DDIs) has become a key component of drug development. PBPK modeling has also been considered as an approach to predict drug disposition in special populations. However, whether models developed and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Metab Dispos
Päätekijät: Huang, Weize, Nakano, Mariko, Sager, Jennifer, Ragueneau-Majlessi, Isabelle, Isoherranen, Nina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637815/
https://ncbi.nlm.nih.gov/pubmed/28860113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.076455
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