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Ketones as directing groups in photocatalytic sp(3) C–H fluorination

The ubiquitous ketone carbonyl group generally deactivates substrates toward radical-based fluorinations, especially sites closest to it. Herein, ketones are used instead to direct aliphatic fluorination using Selectfluor, catalytic benzil, and visible light. Selective β- and γ-fluorination are demo...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Bume, Desta Doro, Pitts, Cody Ross, Ghorbani, Fereshte, Harry, Stefan Andrew, Capilato, Joseph N., Siegler, Maxime A., Lectka, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637129/
https://ncbi.nlm.nih.gov/pubmed/29147517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02703f
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