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Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids

Mortalin (Mot) is a mitochondrial chaperone of the heat shock protein 70 family and it’s pro-proliferative and anti-apoptosis functions could be associated with keloid pathogenesis, and blocking of mortalin and its interaction with p53 might be a potential novel target for the treatment of keloid. T...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Lee, Won Jai, Ahn, Hyo Min, Na, Youjin, Wadhwa, Renu, Hong, JinWoo, Yun, Chae-Ok
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636810/
https://ncbi.nlm.nih.gov/pubmed/29021584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13485-y
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