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Relevance of mortalin to cancer cell stemness and cancer therapy

Mortalin/mtHsp70 is a member of Hsp70 family of proteins. Enriched in a large variety of cancers, it has been shown to contribute to the process of carcinogenesis by multiple ways including inactivation of tumor suppressor p53 protein, deregulation of apoptosis and activation of EMT signaling. In th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yun, Chae-Ok, Bhargava, Priyanshu, Na, Youjin, Lee, Jung-Sun, Ryu, Jihoon, Kaul, Sunil C., Wadhwa, Renu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292728/
https://ncbi.nlm.nih.gov/pubmed/28165047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42016
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