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Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras
Currently, there are no effective therapeutic strategies targeting Kras driven cancers, and therefore, identifying new targeted therapies and overcoming drug resistance have become paramount for effective long-term cancer therapy. We have found that reducing expression of the palmitoyl transferase D...
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| Опубликовано в: : | Biochem Biophys Res Commun |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636688/ https://ncbi.nlm.nih.gov/pubmed/28899783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.09.044 |
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