Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A

BACKGROUND: We have previously shown that palmitoylation is essential for NRAS leukemogenesis, suggesting that targeting RAS palmitoylation may be an effective therapy for NRAS-related cancers. For KRAS-driven cancer, although much research has been focused on the KRAS4B splice variant, which does n...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Zhao, Huanbin, Liu, Ping, Zhang, Ruihong, Wu, Min, Li, Donghe, Zhao, Xuemei, Zhang, Chun, Jiao, Bo, Chen, Bing, Chen, Zhu, Ren, Ruibao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696201/
https://ncbi.nlm.nih.gov/pubmed/26715448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0226-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker