Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions

BACKGROUND: Activating neurotrophic tyrosine receptor kinase (NTRK) fusions, typically detected via nucleic acid based assays, are highly targetable and define certain tumors. Here, we explore the utility of pan-TRK immunohistochemistry (IHC) to detect NTRK fusions. DESIGN: NTRK rearrangements were...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Am J Surg Pathol
Main Authors: Hechtman, Jaclyn F., Benayed, Ryma, Hyman, David M., Drilon, Alexander, Zehir, Ahmet, Frosina, Denise, Arcila, Maria E., Dogan, Snjezana, Klimstra, David S., Ladanyi, Marc, Jungbluth, Achim A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636652/
https://ncbi.nlm.nih.gov/pubmed/28719467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000911
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker