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Applicability of pan-TRK immunohistochemistry for identification of NTRK fusions in lung carcinoma

In the last two decades, various therapies have been introduced for lung carcinoma patients, including tyrosine-kinase inhibitors for different mutations. While some of them are specific to specific tumor types, others, like NTRK1–3 fusions, are found in various solid tumors. The occurrence of an NT...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Strohmeier, Simon, Brcic, Iva, Popper, Helmut, Liegl-Atzwanger, Bernadette, Lindenmann, Jörg, Brcic, Luka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105314/
https://ncbi.nlm.nih.gov/pubmed/33963267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89373-3
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