Pan-Trk immunohistochemistry is a sensitive and specific ancillary tool in diagnosing secretory carcinoma of salivary gland and detecting ETV6-NTRK3 fusion

AIM: Secretory carcinoma (SC) of salivary gland typically harbors ETV6-NTRK3 fusion which can be utilized clinically to assist with diagnosis. Pan-TRK inhibitor therapy has demonstrated drastic responses in patients with NTRK-translocated tumors, including SC. Pan-Trk IHC is emerging as a sensitive...

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Detalhes bibliográficos
Publicado no:Histopathology
Main Authors: Xu, Bin, Rasheed, Mohamed Rizwan Haroon Al, Antonescu, Cristina R., Alex, Deepu, Frosina, Denise, Ghossein, Ronald, Jungbluth, Achim A., Katabi, Nora
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994356/
https://ncbi.nlm.nih.gov/pubmed/31448442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.13981
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