Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish

When activated by the accumulation of unfolded proteins in the endoplasmic reticulum, metazoan IRE1, the most evolutionarily conserved unfolded protein response (UPR) transducer, initiates unconventional splicing of XBP1 mRNA. Unspliced and spliced mRNA are translated to produce pXBP1(U) and pXBP1(S...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Ishikawa, Tokiro, Kashima, Makoto, Nagano, Atsushi J, Ishikawa-Fujiwara, Tomoko, Kamei, Yasuhiro, Todo, Takeshi, Mori, Kazutoshi
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636610/
https://ncbi.nlm.nih.gov/pubmed/28952924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26845
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker