ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish

ATF6α and ATF6β are membrane-bound transcription factors activated by regulated intramembrane proteolysis in response to endoplasmic reticulum (ER) stress to induce various ER quality control proteins. ATF6α- and ATF6β single-knockout mice develop normally, but ATF6α/β double knockout causes embryon...

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Main Authors: Ishikawa, Tokiro, Okada, Tetsuya, Ishikawa-Fujiwara, Tomoko, Todo, Takeshi, Kamei, Yasuhiro, Shigenobu, Shuji, Tanaka, Minoru, Saito, Taro L., Yoshimura, Jun, Morishita, Shinichi, Toyoda, Atsushi, Sakaki, Yoshiyuki, Taniguchi, Yoshihito, Takeda, Shunichi, Mori, Kazutoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639050/
https://ncbi.nlm.nih.gov/pubmed/23447699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-11-0830
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