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Evolutionary diversification of protein–protein interactions by interface add-ons

Cells contain a multitude of protein complexes whose subunits interact with high specificity. However, the number of different protein folds and interface geometries found in nature is limited. This raises the question of how protein–protein interaction specificity is achieved on the structural leve...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Plach, Maximilian G., Semmelmann, Florian, Busch, Florian, Busch, Markus, Heizinger, Leonhard, Wysocki, Vicki H., Merkl, Rainer, Sterner, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635890/
https://ncbi.nlm.nih.gov/pubmed/28923934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707335114
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