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Evolutionary diversification of protein–protein interactions by interface add-ons
Cells contain a multitude of protein complexes whose subunits interact with high specificity. However, the number of different protein folds and interface geometries found in nature is limited. This raises the question of how protein–protein interaction specificity is achieved on the structural leve...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635890/ https://ncbi.nlm.nih.gov/pubmed/28923934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707335114 |
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