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Generation of a stand-alone tryptophan synthase α-subunit by mimicking an evolutionary blueprint
The αββα tryptophan synthase (TS), which is part of primary metabolism, is a paradigm for allosteric communication in multi-enzyme complexes. In particular, the intrinsically low catalytic activity of the α-subunit TrpA is stimulated several hundred-fold by the interaction with the β-subunit TrpB1....
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293203/ https://ncbi.nlm.nih.gov/pubmed/31090986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900323 |
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