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Inflammatory activation of human cardiac fibroblasts leads to altered calcium signaling, decreased connexin 43 expression and increased glutamate secretion

Cardiac fibroblasts, which are abundant in heart tissue, are involved not only in extracellular matrix homeostasis and repair, but also in cardiac remodeling after a myocardial infarction that, in turn, can lead to loss of cardiac function and heart failure. Ca(2+) signaling is functionally importan...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Skiöldebrand, Eva, Lundqvist, Annika, Björklund, Ulrika, Sandstedt, Mikael, Lindahl, Anders, Hansson, Elisabeth, Hultén, Lillemor Mattsson
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633159/
https://ncbi.nlm.nih.gov/pubmed/29022008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00406
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