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The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation

Ischemic heart disease is a major cause of death and morbidity and the search for novel therapeutic targets is still required. We have previously shown that the enzyme arachidonate 15 lipoxygenase (ALOX15), which catalyzes the conversion of arachidonic acid to 15-hydroxy eicosatetraenoic acid (15-HE...

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Publicat a:PLoS One
Autors principals: Lundqvist, Annika, Sandstedt, Mikael, Sandstedt, Joakim, Wickelgren, Ruth, Hansson, Göran I., Jeppsson, Anders, Hultén, Lillemor Mattsson
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994938/
https://ncbi.nlm.nih.gov/pubmed/27552229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161629
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