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The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation

Ischemic heart disease is a major cause of death and morbidity and the search for novel therapeutic targets is still required. We have previously shown that the enzyme arachidonate 15 lipoxygenase (ALOX15), which catalyzes the conversion of arachidonic acid to 15-hydroxy eicosatetraenoic acid (15-HE...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Lundqvist, Annika, Sandstedt, Mikael, Sandstedt, Joakim, Wickelgren, Ruth, Hansson, Göran I., Jeppsson, Anders, Hultén, Lillemor Mattsson
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994938/
https://ncbi.nlm.nih.gov/pubmed/27552229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161629
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