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The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation

Ischemic heart disease is a major cause of death and morbidity and the search for novel therapeutic targets is still required. We have previously shown that the enzyme arachidonate 15 lipoxygenase (ALOX15), which catalyzes the conversion of arachidonic acid to 15-hydroxy eicosatetraenoic acid (15-HE...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lundqvist, Annika, Sandstedt, Mikael, Sandstedt, Joakim, Wickelgren, Ruth, Hansson, Göran I., Jeppsson, Anders, Hultén, Lillemor Mattsson
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994938/
https://ncbi.nlm.nih.gov/pubmed/27552229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161629
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