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Serotonin-evoked cytosolic Ca(2+) release and opioid receptor expression are upregulated in articular cartilage chondrocytes from osteoarthritic joints in horses

Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular cartilage could represent novel therapeutic targets. Acute and chronic stages of OA indicate different metabolic abilities of the chondrocytes depending on inflammatory state....

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發表在:Vet Anim Sci
Main Authors: Skiöldebrand, Eva, Ley, Cecilia, Björklund, Ulrika, Lindahl, Anders, Hansson, Elisabeth
格式: Artigo
語言:Inglês
出版: Elsevier 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386637/
https://ncbi.nlm.nih.gov/pubmed/32734095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vas.2019.100078
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