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Serotonin-evoked cytosolic Ca(2+) release and opioid receptor expression are upregulated in articular cartilage chondrocytes from osteoarthritic joints in horses

Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular cartilage could represent novel therapeutic targets. Acute and chronic stages of OA indicate different metabolic abilities of the chondrocytes depending on inflammatory state....

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Publicat a:Vet Anim Sci
Autors principals: Skiöldebrand, Eva, Ley, Cecilia, Björklund, Ulrika, Lindahl, Anders, Hansson, Elisabeth
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386637/
https://ncbi.nlm.nih.gov/pubmed/32734095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vas.2019.100078
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