SINGLE STAGE TANDEM MASS SPECTROMETRY ASSIGNMENT OF THE C-5 URONIC ACID STEREOCHEMISTRY IN HEPARAN SULFATE TETRASACCHARIDES USING ELECTRON DETACHMENT DISSOCIATION

The analysis of heparan sulfate (HS) glycosaminoglycans presents many challenges, due to the high degree of structural heterogeneity arising from their non-template biosynthesis. Complete structural elucidation of glycosaminoglycans necessitates the unambiguous assignments of sulfo modifications and...

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Bibliographic Details
Published in:J Am Soc Mass Spectrom
Main Authors: Agyekum, Isaac, Zong, Chengli, Boons, Geert-Jan, Amster, I. Jonathan
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632119/
https://ncbi.nlm.nih.gov/pubmed/28389983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1643-x
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