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MULTIVARIATE ANALYSIS OF ELECTRON DETACHMENT DISSOCIATION AND INFRARED MULTIPHOTON DISSOCIATION MASS SPECTRA OF HEPARAN SULFATE TETRASACCHARIDES DIFFERING ONLY IN HEXURONIC ACID STEREOCHEMISTRY

The structural characterization of glycosaminoglycan (GAG) carbohydrates by mass spectrometry has been a long standing analytical challenge due to the inherent heterogeneity of these biomolecules, specifically polydispersity, variability in sulfation, and hexuronic acid stereochemistry. Recent advan...

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Bibliographic Details
Main Authors: Oh, Han Bin, Leach, Franklin E., Arungundram, Sailaja, Al-Mafraji, Kanar, Venot, Andre, Boons, Geert-Jan, Amster, I. Jonathan
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192014/
https://ncbi.nlm.nih.gov/pubmed/21472576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-010-0047-y
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