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SINGLE STAGE TANDEM MASS SPECTROMETRY ASSIGNMENT OF THE C-5 URONIC ACID STEREOCHEMISTRY IN HEPARAN SULFATE TETRASACCHARIDES USING ELECTRON DETACHMENT DISSOCIATION

The analysis of heparan sulfate (HS) glycosaminoglycans presents many challenges, due to the high degree of structural heterogeneity arising from their non-template biosynthesis. Complete structural elucidation of glycosaminoglycans necessitates the unambiguous assignments of sulfo modifications and...

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Détails bibliographiques
Publié dans:J Am Soc Mass Spectrom
Auteurs principaux: Agyekum, Isaac, Zong, Chengli, Boons, Geert-Jan, Amster, I. Jonathan
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632119/
https://ncbi.nlm.nih.gov/pubmed/28389983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1643-x
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