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SINGLE STAGE TANDEM MASS SPECTROMETRY ASSIGNMENT OF THE C-5 URONIC ACID STEREOCHEMISTRY IN HEPARAN SULFATE TETRASACCHARIDES USING ELECTRON DETACHMENT DISSOCIATION
The analysis of heparan sulfate (HS) glycosaminoglycans presents many challenges, due to the high degree of structural heterogeneity arising from their non-template biosynthesis. Complete structural elucidation of glycosaminoglycans necessitates the unambiguous assignments of sulfo modifications and...
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| Udgivet i: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632119/ https://ncbi.nlm.nih.gov/pubmed/28389983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1643-x |
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