Genetic depletion of adipocyte creatine metabolism inhibits diet-induced thermogenesis and drives obesity

Diet-induced thermogenesis is an important homeostatic mechanism that limits weight gain in response to caloric excess and contributes to the relative stability of body weight in most individuals. We previously demonstrated that creatine enhances energy expenditure through stimulation of mitochondri...

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Détails bibliographiques
Publié dans:Cell Metab
Auteurs principaux: Kazak, Lawrence, Chouchani, Edward T., Lu, Gina Z., Jedrychowski, Mark P., Bare, Curtis J., Mina, Amir, Kumari, Manju, Zhang, Song, Vuckovic, Ivan, Laznik-Bogoslavski, Dina, Dzeja, Petras, Banks, Alexander S., Rosen, Evan D., Spiegelman, Bruce M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629120/
https://ncbi.nlm.nih.gov/pubmed/28844881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.009
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