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Bioinspired enantioselective synthesis of crinine-type alkaloids via iridium-catalyzed asymmetric hydrogenation of enones

A bioinspired enantioselective synthesis of crinine-type alkaloids has been developed by iridium-catalyzed asymmetric hydrogenation of racemic cycloenones. The method features a biomimetic stereodivergent resolution of the substrates bearing a remote arylated quaternary stereocenter. Using this prot...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Zuo, Xiao-Dong, Guo, Shu-Min, Yang, Rui, Xie, Jian-Hua, Zhou, Qi-Lin
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628337/
https://ncbi.nlm.nih.gov/pubmed/28989653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02112g
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