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Highly Enantioselective Iridium-Catalyzed Hydrogenation of Conjugated Trisubstituted Enones

[Image: see text] Asymmetric hydrogenation of conjugated enones is one of the most efficient and straightforward methods to prepare optically active ketones. In this study, chiral bidentate Ir–N,P complexes were utilized to access these scaffolds for ketones bearing the stereogenic center at both th...

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Vydáno v:Org Lett
Hlavní autoři: Peters, Bram B. C., Jongcharoenkamol, Jira, Krajangsri, Suppachai, Andersson, Pher G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884017/
https://ncbi.nlm.nih.gov/pubmed/33351634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c04012
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