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Asymmetric synthesis of 1,2-fluorohydrin: iridium catalyzed hydrogenation of fluorinated allylic alcohol

We have developed a simple protocol for the preparation of 1,2-fluorohydrin by asymmetric hydrogenation of fluorinated allylic alcohols using an efficient azabicyclo thiazole-phosphine iridium complex. The iridium-catalyzed asymmetric synthesis of chiral 1,2-fluorohydrin molecules was carried out at...

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Ponra, Sudipta, Yang, Jianping, Wu, Haibo, Rabten, Wangchuk, Andersson, Pher G.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society of Chemistry 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162319/
https://ncbi.nlm.nih.gov/pubmed/34094359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04032k
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