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Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2
Pulmonary arterial stiffness is an independent risk factor for mortality in pulmonary hypertension (PH) and plays a critical role in PH pathophysiology. Our laboratory has recently demonstrated arterial stiffening early in experimental PH, along with evidence for a mechanobiological feedback loop by...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Am J Physiol Lung Cell Mol Physiol |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Physiological Society
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625262/ https://ncbi.nlm.nih.gov/pubmed/28642262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00173.2017 |
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