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Glutamine‐utilizing transaminases are a metabolic vulnerability of TAZ/YAP‐activated cancer cells

The transcriptional regulators TAZ and YAP (TAZ/YAP) have emerged as pro‐tumorigenic factors that drive many oncogenic traits, including induction of cell growth, resistance to cell death, and activation of processes that promote migration and invasion. Here, we report that TAZ/YAP reprogram cellula...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Yang, Chih‐Sheng, Stampouloglou, Eleni, Kingston, Nathan M, Zhang, Liye, Monti, Stefano, Varelas, Xaralabos
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989844/
https://ncbi.nlm.nih.gov/pubmed/29661856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643577
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