Glutamine‐utilizing transaminases are a metabolic vulnerability of TAZ/YAP‐activated cancer cells

The transcriptional regulators TAZ and YAP (TAZ/YAP) have emerged as pro‐tumorigenic factors that drive many oncogenic traits, including induction of cell growth, resistance to cell death, and activation of processes that promote migration and invasion. Here, we report that TAZ/YAP reprogram cellula...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Yang, Chih‐Sheng, Stampouloglou, Eleni, Kingston, Nathan M, Zhang, Liye, Monti, Stefano, Varelas, Xaralabos
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Scientific Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989844/
https://ncbi.nlm.nih.gov/pubmed/29661856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643577
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