Glutamine‐utilizing transaminases are a metabolic vulnerability of TAZ/YAP‐activated cancer cells

The transcriptional regulators TAZ and YAP (TAZ/YAP) have emerged as pro‐tumorigenic factors that drive many oncogenic traits, including induction of cell growth, resistance to cell death, and activation of processes that promote migration and invasion. Here, we report that TAZ/YAP reprogram cellula...

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Bibliografiska uppgifter
I publikationen:EMBO Rep
Huvudupphovsmän: Yang, Chih‐Sheng, Stampouloglou, Eleni, Kingston, Nathan M, Zhang, Liye, Monti, Stefano, Varelas, Xaralabos
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Scientific Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989844/
https://ncbi.nlm.nih.gov/pubmed/29661856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643577
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