Glutamine‐utilizing transaminases are a metabolic vulnerability of TAZ/YAP‐activated cancer cells

The transcriptional regulators TAZ and YAP (TAZ/YAP) have emerged as pro‐tumorigenic factors that drive many oncogenic traits, including induction of cell growth, resistance to cell death, and activation of processes that promote migration and invasion. Here, we report that TAZ/YAP reprogram cellula...

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書目詳細資料
發表在:EMBO Rep
Main Authors: Yang, Chih‐Sheng, Stampouloglou, Eleni, Kingston, Nathan M, Zhang, Liye, Monti, Stefano, Varelas, Xaralabos
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
主題:
Scientific Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989844/
https://ncbi.nlm.nih.gov/pubmed/29661856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643577
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