Multiple DNA-binding modes for the ETS family transcription factor PU.1

The eponymous DNA-binding domain of ETS (E26 transformation-specific) transcription factors binds a single sequence-specific site as a monomer over a single helical turn. Following our previous observation by titration calorimetry that the ETS member PU.1 dimerizes sequentially at a single sequence-...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Esaki, Shingo, Evich, Marina G., Erlitzki, Noa, Germann, Markus W., Poon, Gregory M. K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Molecular Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625037/
https://ncbi.nlm.nih.gov/pubmed/28790174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.798207
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