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Distinct Roles for Interfacial Hydration in Site-Specific DNA Recognition by ETS-Family Transcription Factors

The ETS family of transcription factors is a functionally heterogeneous group of gene regulators that share a structurally conserved, eponymous DNA-binding domain. Unlike other ETS homologues, such as Ets-1, DNA recognition by PU.1 is highly sensitive to its osmotic environment due to excess interfa...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Xhani, Suela, Esaki, Shingo, Huang, Kenneth, Erlitzki, Noa, Poon, Gregory M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541755/
https://ncbi.nlm.nih.gov/pubmed/28296403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00325
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