T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy

HIV-specific CD8(+) T-cell responses limit viral replication in untreated infection. After the initiation of antiretroviral therapy (ART), these responses decay and the infected cell population that remains is commonly considered to be invisible to T-cells. We hypothesized that HIV antigen recogniti...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Thomas, Allison S., Jones, Kimberley L., Gandhi, Rajesh T., McMahon, Deborah K., Cyktor, Joshua C., Chan, Dora, Huang, Szu-Han, Truong, Ronald, Bosque, Alberto, Macedo, Amanda B., Kovacs, Colin, Benko, Erika, Eron, Joseph J., Bosch, Ronald J., Lalama, Christina M., Simmens, Samuel, Walker, Bruce D., Mellors, John W., Jones, R. Brad
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624641/
https://ncbi.nlm.nih.gov/pubmed/28931091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006629
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki